04/26/22Salk Institute Cellular regeneration therapy restores damaged liver tissue faster than ever Read more

04/22/22Salk Institute An ocean in your brain: interacting brain waves key to how we process information LA JOLLA—For years, the brain has been thought of as a biological computer that processes information through traditional circuits, whereby data zips straight from one cell to another. While that model is still accurate, a new study led by Salk Professor Thomas Albright and Staff Scientist Sergei Gepshtein shows that there’s also a second, very different way that the brain parses information: through the interactions of waves of neural activity. The findings, published in Science Advances on April 22, 2022, help researchers better understand how the brain processes information. Read more

04/21/22Salk Institute The protein that keeps the pancreas from digesting itself LA JOLLA—Every day, your pancreas produces about one cup of digestive juices, a mixture of molecules that can break down the food you eat. But if these powerful molecules become activated before they make their way to the gut, they can damage the pancreas itself—digesting the very cells that created them, leading to the painful inflammation known as pancreatitis, and predisposing a person to pancreatic cancer. Read more

04/13/22Sanford Burnham Prebys Padres Pedal the Cause 2022: Team Sanford Burnham Prebys raises more than $21,000 for cancer research Last weekend, Sanford Burnham Prebys helped support local cancer research by participating in Padres Pedal the Cause. Read more

04/06/22Sanford Burnham Prebys Naturally occurring combinations of receptors from single cell transcriptomics in endothelial cells Paper of the Week Read more

03/24/22Salk Institute Salk scientist Tony Hunter receives 2022 AACR Lifetime Achievement Award in Cancer Research LA JOLLA—Salk Institute Professor Tony Hunter will receive the 2022 American Association for Cancer Research (AACR) Award for Lifetime Achievement in Cancer Research at the April annual meeting of AACR, the largest cancer research organization in the world dedicated to preventing and curing all cancers. This major award is a significant recognition of Hunter’s contributions to cancer research, which have led to the development of the highly effective leukemia drug GleevecTM. Read more

03/21/22UCSD New Screening Tool IDs 95 Percent of Stage 1 Pancreatic Cancer UC San Diego study finds new screening tool flags 95 percent of stage 1 pancreatic cancers. Read more

03/21/22UCSD Transplant, Cancer Patients Among First to Get Evusheld at UC San Diego Health UC San Diego Health is now administering Evusheld to eligible, immunocompromised patients to protect against the COVID-19 virus. Read more

03/15/22Sanford Burnham Prebys Tricking the body to treat breast cancer Stimulating immune responses can help the body fight cancer and improve the effects of other treatments. Read more

03/11/22Salk Institute Salk scientists receive 2022 Mark Foundation Endeavor Award to study lung cancer LA JOLLA—Professors Reuben Shaw, Susan Kaech, Christian Metallo and Alan Saghatelian have received a 2022 Mark Foundation for Cancer Research Endeavor Award to support their research exploring the metabolic changes that help lung cancers develop. The $3 million Endeavor Award promotes collaborative science to tackle some of the toughest challenges in cancer research. The Salk team—one of four teams chosen out of nearly 200 applications submitted by institutions around the world—hopes their work will lead to the development of more effective lung cancer treatments. Read more

03/09/22Salk Institute New technology enables unprecedented glimpse inside single brain cells LA JOLLA—Salk Institute researchers have developed a new genomic technology to simultaneously analyze the DNA, RNA and chromatin—a combination of DNA and protein—from a single cell. The method, which took five years to develop, is an important step forward for large collaborations where multiple teams are working simultaneously to classify thousands of new cell types. The new technology, published in Cell Genomics on March 9, 2022, will help streamline analyses. Read more

03/07/22Salk Institute Cellular rejuvenation therapy safely reverses signs of aging in mice LA JOLLA—Age may be just a number, but it’s a number that often carries unwanted side effects, from brittle bones and weaker muscles to increased risks of cardiovascular disease and cancer. Now, scientists at the Salk Institute, in collaboration with Genentech, a member of the Roche group, have shown that they can safely and effectively reverse the aging process in middle-aged and elderly mice by partially resetting their cells to more youthful states. Read more

03/07/22Salk Institute Tiny worms make complex decisions, too LA JOLLA—How does an animal make decisions? Scientists have spent decades trying to answer this question by focusing on the cells and connections of the brain that might be involved. Salk scientists are taking a different approach—analyzing behavior, not neurons. They were surprised to find that worms can take multiple factors into account and choose between two different actions, despite having only 302 neurons compared to approximately 86 billion in humans. Read more

02/24/22UCSD Alternative Approach Uses Sound Waves to Treat Prostate Cancer UC San Diego Health is the first hospital system in San Diego County to employ high-intensity, focused ultrasound (HIFU) for minimally invasive prostate cancer treatment. Read more

02/17/22UCSD UC San Diego Health: Excellence in Medication Safety, Pharmacy Practice UC San Diego Health has become the first organization recognized as a Certified Center of Excellence in Medication-Use Safety and Pharmacy Practice by the American Society of Health-System Pharmacists ... Read more

02/15/22UCSD Pandemic Upends Breast Cancer Diagnoses UC San Diego Health researchers surveyed and compared early- and late-stage breast and colorectal cancer diagnoses in patients in pre-pandemic 2019 and in 2020, the first full year of the COVID-19 pan ... Read more